Marriage and Sex in the Age of Ozempic

Summary of Marriage and Sex in the Age of Ozempic

by The New York Times

37mOctober 7, 2025

Summary — "Marriage and Sex in the Age of Ozempic" (The New York Times, The Daily)

Overview

This episode examines how GLP‑1 weight‑loss medications (commonly associated with Ozempic, Wegovy, etc.) can transform not only bodies but intimate relationships. Through the story of Jean and Javier — a couple married 15 years — reporter Lisa (guest) explores the medical effects of the drugs, the social and career consequences of rapid weight loss, and the unexpected strains these changes can place on marriage and sex life.

Key points & main takeaways

  • How the drugs work

    • GLP‑1 medications reduce appetite and food cravings, producing fast, large weight loss for people who have long struggled with dieting.
    • They also commonly reduce desire for alcohol; researchers are investigating GLP‑1s for addiction treatment.
  • Rapid physical change has wide ripple effects

    • Jean lost ~60 pounds in eight months; clothing, social treatment, and workplace opportunities changed quickly.
    • External reactions (better treatment, new opportunities) often make the transformation feel both liberating and disorienting.
  • Emotional/psychological shifts are as consequential as physical ones

    • Weight loss reduced Jean’s "food noise" and empowered her to set boundaries and decline activities she previously did to please others.
    • That newfound agency changed how she engaged socially and sexually.
  • Impact on sexual intimacy and marriage

    • Jean and Javier stopped having sex after she began medication; multiple factors are discussed (menopause, antidepressants, medication effects, changing desires).
    • For Jean, declining sex can represent boundary setting and reassessing what she wants; for Javier, it feels like loss and confusion (he misses the former “voluptuousness”).
    • Attempts at therapeutic exercises (non‑erogenous touch, staged re‑introduction) met with limited success.
  • Relationship resilience depends on flexibility

    • Couples who adapt best are those willing to renegotiate rituals and expectations rather than insist things remain unchanged.
    • Therapy, patience, empathy, and open communication help, but outcomes vary and may include permanent changes in sexual dynamics.

Notable quotes / insights

  • Jean: “This is one of the best things that I’ve done for myself... I will maintain this for life.”
  • Javier: “I need a roadmap… I don’t recognize you.”
  • On past dynamics: “We were one ship.” (Describing the sense of unity before the change.)
  • Reporter/therapist insight: Couples who aren’t rigid in their expectations manage the transition better.
  • Concept highlighted: “food noise” — a non‑physiological, compulsive drive to eat that some patients describe.

Topics discussed

  • GLP‑1 medications (mechanism and effects)
  • Rapid weight loss and social perception
  • Career and public-facing opportunities after weight loss
  • Reduced appetite for alcohol and implications
  • Sexual desire, libido, and changes after weight loss
  • Boundary setting, self-image, and empowerment
  • Couples therapy techniques for sexual reconnection (phase-based touch exercises)
  • Emotional labor in long-term relationships and renegotiation of unspoken contracts

Action items / Recommendations

For individuals considering or on GLP‑1 medications:

  • Discuss potential psychosocial and sexual side effects with your prescribing clinician (not just metabolic effects).
  • Consider counseling or support focused on body image and identity changes during rapid weight loss.

For partners and couples:

  • Expect that rapid body changes can unearth latent relationship dynamics — anticipate renegotiation of roles and rituals.
  • Practice explicit communication: share feelings, losses, and desires without assuming motives.
  • Use couples therapy constructively: try staged intimacy exercises, but allow time and don’t pressure.
  • Cultivate flexibility: be prepared to invent new shared rituals and forms of intimacy.

For clinicians and therapists:

  • Screen for relationship stressors when prescribing GLP‑1s; counsel patients and partners about possible impacts.
  • Coordinate care that includes mental health or couples therapy when rapid physiological changes occur.

Bottom line

Weight‑loss drugs like GLP‑1s can be life‑changing medically and psychologically. Alongside benefits (less “food noise,” improved health, new opportunities) these medications can disrupt established relationship patterns, sexual dynamics, and identity. Successful adaptation typically requires communication, empathy, flexibility, and sometimes professional support — and acceptance that some aspects (including sexual patterns) may not return to how they were.