Big mysteries explained through your senses

Summary of Big mysteries explained through your senses

by NPR

50m•September 18, 2026

Overview of Big mysteries explained through your senses

This episode of TED Radio Hour explores how human senses help us understand enormous, invisible, or hard-to-grasp phenomena—from the early universe to brain disease, from climate change to artificial intelligence. Through conversations with astronomer Mark Whittle, smell researcher Paula/Polly Joseph, and artist Yi-Yun Kang, the show argues that sound, smell, and sight can make abstract science and hidden threats more tangible, emotional, and actionable.

Sound: Hearing the origins of the universe

Astronomer Mark Whittle explains that the Big Bang itself was silent, because sound requires matter to travel through. But once the young universe filled with hot gas, sound waves began to ripple through it during an “acoustic era” that lasted about 400,000 years.

Key ideas

  • The early universe behaved like a giant musical instrument.
  • Gravity created compressions and rarefactions in the gas, generating sound waves.
  • Those waves are no longer audible in real time, but scientists can translate them into sound.
  • The cosmic microwave background is key evidence of the early universe: light stretched by expansion into microwaves over billions of years.
  • Whittle uses harmonics from the microwave background to reveal a structure similar to a voice or instrument.

Notable insight

  • The “music” of the universe is not literal melody, but it does contain fundamental tones and harmonics—a pattern that helped scientists understand the structure of the cosmos.

Turning cosmic data into music

Whittle describes how satellite missions like COBE, WMAP, and Planck revealed increasingly detailed patterns in the cosmic microwave background.

What he did

  • Translated wave data into sound and then into musical notes.
  • Worked with artist/composer collaborators to turn the sequence into a choir and organ composition.
  • Used art to help non-scientists emotionally connect with deep cosmological history.

Bigger takeaway

  • The same material that once made up the early universe now makes up stars, planets, and human beings—meaning the universe can, through us, become aware of its own beginnings.

Smell: An early warning system for the body

Polly Joseph, a senior investigator at the NIH and co-director of the National Smell and Taste Center, discusses smell as both a survival tool and a diagnostic clue.

Key ideas

  • Smell helps detect smoke, toxins, spoiled food, predators, and other dangers.
  • It can also reveal neurological disease early—sometimes years before other symptoms.

Important examples

  • Joseph noticed her mother-in-law’s food tasted unusually salty or sweet, and testing revealed a decreased sense of smell.
  • That loss helped lead to a diagnosis of frontotemporal dementia.
  • Reduced smell is also seen early in Alzheimer’s, Parkinson’s, and other neurodegenerative diseases.

Smell loss, COVID, and quality of life

The episode emphasizes that smell loss is not trivial.

Real-world impact

  • A firefighter who lost his smell after COVID could no longer safely do his job.
  • A chef lost an essential part of their livelihood and identity.
  • Some people develop parosmia, where familiar smells become distorted—coffee may smell like burning garbage, for example.

Treatment and research

  • There are few treatments for smell loss.
  • Olfactory training can help some people, but not all.
  • Researchers are studying the brain mechanisms behind smell distortion using fMRI.
  • Joseph argues smell should be screened in primary care, just like vision and hearing.

Smell, food, and metabolic health

Joseph also connects smell research to obesity and alcohol use disorder.

Main points

  • Alcohol smell can trigger cravings.
  • Researchers are studying how long-term drinking affects smell and whether it recovers with abstinence.
  • For people taking GLP-1 medications, the main changes may involve food cues, sweetness detection thresholds, and cravings, not necessarily smell itself.
  • The sensory experience of food includes more than taste: it also involves smell, texture, and thought patterns about eating.

Sight and art: Making invisible systems visible

Artist Yi-Yun Kang uses multimedia art to translate invisible systems—like climate data and AI—into physical, emotional experiences.

Her approach

  • She says the goal is to “render the invisible visible.”
  • Her work turns satellite data into immersive visual art, especially around freshwater loss.
  • In one project, red and blue planetary visuals show the Earth losing freshwater over time, making a data crisis feel immediate and human.

On AI

  • Kang is concerned that AI’s clean user interfaces hide its complexity.
  • She creates immersive installations that let people step inside the “mind” of a machine.
  • Her work reflects both excitement and anxiety about AI’s role in the future.

Main takeaways

  • Senses are not just for daily survival; they are tools for understanding huge, otherwise invisible systems.
  • Sound can help us comprehend the origin and structure of the universe.
  • Smell can act as an early warning system for neurological disease and major life changes.
  • Sight and art can make climate change and AI feel concrete enough to confront.
  • Across all segments, the episode suggests a profound idea: the universe made us from its own material, and through our senses, it can begin to understand itself.

Featured voices

  • Mark Whittle — astrophysicist, University of Virginia
  • Polly Joseph — NIH researcher and co-director of the National Smell and Taste Center
  • Yi-Yun Kang — multimedia artist based in Seoul
  • Hosted by Manoush Zomorodi on TED Radio Hour from NPR