Mark Cuban on High Drug Prices, Taxing Billionaires, and 2028

Summary of Mark Cuban on High Drug Prices, Taxing Billionaires, and 2028

by New York Magazine

1h 15m•August 21, 2026

Overview of Pivot with Mark Cuban

In this episode of Pivot, Kara Swisher talks with Mark Cuban about the biggest economic and political pressure points shaping the U.S. right now: prescription drug pricing, the broken incentives in healthcare, the limits of billionaire taxation, the exploding value of sports franchises, and why he still doesn’t want to run for president. Cuban argues that the fastest way to lower costs is to eliminate middlemen, increase transparency, and use AI to expose bad contracts—especially in healthcare.

Healthcare and Prescription Drug Pricing

Why drug prices are finally falling

  • Cuban says recent price drops are being driven by a mix of factors:
    • Medicare’s ability to negotiate some drug prices under the Biden-era IRA
    • Increased competition from biosimilars (generic-like versions of injectable drugs)
    • More volume flowing through Cost Plus Drugs, which lowers costs further because of the company’s cost-plus pricing model
  • He credits Trump for pushing some price reductions too, especially on:
    • IVF-related drugs
    • GLP-1 medications in some Medicare contexts

How TrumpRx and Cost Plus Drugs work together

  • Cuban explains that TrumpRx is essentially a referral/price-comparison portal:
    • It shows prices for certain drugs
    • If Cost Plus is cheapest, users are routed there
  • He says the partnership has increased traffic and sales, and that his company has lowered prices on more than 200 medications since launch.

Why the system is broken

Cuban argues that healthcare costs are inflated by opaque, layered intermediaries:

  • PBMs (pharmacy benefit managers)
  • insurers
  • third-party administrators
  • co-pay “optimizers”
  • consultants and related subsidiaries

His core argument:

  • These middlemen control formularies and rebate structures
  • They create pricing confusion and information asymmetry
  • Doctors and patients are stuck with denials, prior authorizations, and hidden fees

What he wants changed

  • Remove PBM control over formularies
  • Push employers and governments to audit their healthcare contracts
  • Use AI tools like Claude or ChatGPT to identify where contracts are exploitative
  • Encourage more use of pass-through PBMs instead of legacy giants

AI, Transparency, and Corporate Contracts

AI as a practical weapon

  • Cuban says AI is most useful right now in contract analysis:
    • put large healthcare/benefits contracts into an LLM
    • ask: “Where am I getting screwed?”
  • He claims companies are often shocked by how much money they’re losing to hidden charges and loopholes.

His broader warning about AI and platforms

  • Cuban is sharply critical of Meta/Facebook:
    • He says it allows AI-generated scams using his likeness to sell fake diabetes “cures”
    • He sees this as a cultural problem, not just a moderation issue
  • He also criticizes YouTube and other platforms for enabling AI audio piracy.

Billionaire Tax Proposal in California

Cuban’s critique

  • He pushes back hard on a proposed 5% one-time tax on billionaires in California.
  • His main objection: many billionaires are asset-rich but cash-poor.
    • Their wealth is tied up in private or illiquid stock
    • They may not have enough liquidity to pay a huge one-time tax without selling shares
  • He calls the proposed loan mechanism “insane,” because it would effectively have the state lend them money so they can pay the tax back immediately.

Better alternatives, in his view

Cuban suggests:

  • an alternative minimum tax
  • more realistic capital-gains timing
  • reforming healthcare and Medicaid rules
  • raising revenue through less distortionary means than taxing illiquid founders directly

Broader economic concern

  • He says the bigger inflation driver is the deficit and interest rates
  • He warns that higher rates hurt:
    • stock prices
    • asset values
    • consumers at every level, especially those already struggling

Sports Teams as Vanity Assets

The Lakers sale

Cuban discusses the complex sale of the L.A. Lakers and says sports franchises are now:

  • vanity assets
  • financial engineering assets
  • increasingly tied to private equity and broader market narratives

Why teams are so valuable now

He argues their value comes from:

  • arena real estate
  • concerts and events
  • TV and streaming rights
  • the ability to drive subscriptions and reduce churn for media companies

Jeanie Buss’s role

  • Cuban praises Jeanie Buss as someone who genuinely cares about fans.
  • He thinks the best outcome would be a deal where she:
    • keeps control for a limited period
    • then sells on a pre-agreed timeline

Crypto, Chips, and Asset-Class Hype

Bitcoin and crypto skepticism

  • Cuban says he sold most of his Bitcoin.
  • His view:
    • Bitcoin was supposed to hedge inflation and geopolitical instability
    • But that narrative hasn’t really played out
    • Many crypto projects became speculative or outright scams

Chips as the next narrative

  • He thinks chips could become the next major asset class:
    • Nvidia, AMD, Google TPUs, Amazon chips, etc.
  • He likens them to an asset that can be:
    • tokenized
    • monetized through contracts
    • sold as rights to future economic output
  • His core idea: the “story” matters as much as the underlying economics.

Why Mark Cuban Won’t Run for President

His answer: he can be more effective outside government

Cuban says he doesn’t want to run because:

  • he lacks the patience and temperament for the job
  • the presidency is too constrained by laws, bureaucracy, and political coalitions
  • as an entrepreneur, he can move faster and make direct changes

Where he thinks he can have real impact

  • Cost Plus Drugs
  • Cost Plus Wellness
  • direct corporate pressure
  • contract audits
  • public advocacy

He says he can call CEOs out publicly and actually force change, which he sees as more effective than working inside the system.

Political Predictions and Final Thoughts

Mark Cuban’s 2028/next-wave political instinct

  • He’s optimistic about James Talarico as a rising political figure.
  • He sees Talarico as:
    • honest
    • trustworthy
    • willing to take politically risky positions

His final warning about media and algorithms

Cuban closes by returning to a recurring theme:

  • whoever controls the algorithm shapes public perception
  • platforms like Meta are, in his view, too willing to tolerate abuse, scams, and manipulation
  • his broader message is that transparency and accountability are the only real fixes

Key Takeaways

  • Healthcare costs are driven less by doctors and more by middlemen.
  • AI can be a powerful tool for exposing exploitative contracts.
  • Billionaire taxation is more complicated than it sounds because wealth is often illiquid.
  • Sports franchises are now financial + narrative assets, not just teams.
  • Cuban believes he can do more outside politics than inside it.

Practical Advice from Cuban

For employers and executives

  • Audit health insurance and PBM contracts immediately
  • Use AI to identify hidden fees and bad terms
  • Consider alternatives to legacy PBMs

For consumers

  • Compare drug prices directly
  • Use transparent pricing services when available
  • Be skeptical of opaque insurance and benefit structures

For policymakers

  • Focus on transparency and structural reform
  • Don’t assume simple tax proposals solve liquidity and incentive problems
  • Target intermediaries that add cost without adding value